Lifestyle and socio-economic changes due to urbanization and modernization, especially in big cities in Indonesia, are the cause of an increase in the prevalence of degenerative diseases. Several types of diseases are included in the group of degenerative diseases such as Diabetes Mellitus (DM), coronary heart disease, hypertension, hyperlipidemia and so on. Diabetes Mellitus is one of the non-communicable diseases that will increase in number in the future. This is presumably due to changes in people's diets, which consume more foods that contain protein, fat, sugar, salt, and contain little fiber.

Hyperglycemia, or elevated blood sugar is the main effect of uncontrolled diabetes and in the long term can cause serious damage to nerves and blood vessels. Diabetes Mellitus has a clinical syndrome characterized by polyuria, polydipsia and polyphagia, accompanied by an increase in blood glucose levels or hyperglycemia (fasting glucose level 126 mg/dl or postprandial 200 mg/dl or temporary glucose ≥ 200 mg/dl).

In coronary heart disease, cerebrovascular disease and peripheral arterial disease, it can result in impaired blood vessel function. This condition can result in insufficient blood supply to the organs. There are several risk factors that lead to vascular disease. Some of them are smoking, unhealthy eating lifestyle, lack of physical activity, high blood pressure, diabetes and dyslipidemia. However, there are also other factors that also influence such as genetic and environmental factors.

There is a similar structure of vitamin C with glucose so that it can replace it in several chemical reactions and is thus effective for preventing nonenzymatic glycosylation of proteins. Vitamin C belongs to the group of antioxidant vitamins that are able to ward off various free radicals. Vitamin C is the most important anti-oxidant in plasma. This vitamin is soluble in water and scavenges free radicals and prevents the entry of free radicals into LDL Cholesterol.

Research from Deakin University found that taking 500 milligrams of vitamin C twice daily can help people with type 2 diabetes by lowering the rise in blood sugar levels throughout the day and minimizing spikes in blood sugar levels after meals. Vitamin C is also good for heart health.

This is very important because hyperglycemia is a risk factor for heart disease in people with type 2 diabetes.

Previously, it was found that vitamin C is good for helping heal a weak immune system, improving skin health, increasing mineral absorption, lowering the risk of gout, fighting colds and flu, lowering the risk of stroke, and improving physical performance.

The important things in controlling diabetes are exercise, eating nutritious foods, and taking medication that has been recommended by a doctor.

The antioxidant properties of vitamin C can help ward off the high levels of free radicals found in people with diabetes, and it's encouraging to see the benefits of a number of common co-morbidities, such as high blood pressure.

Reference:

Diabetes Nsw & Act. Vitamin C found to help Type 2
Diabetes.co.uk. Vitamin C linked to reduced glucose levels in type 2 diabetes

Frykberb Robert G.(2002) Risk Factor, Pathogenesis and Management of Diabetik Foot Ulcers, Des Moines University, Iowa.
Journal Diabetes, Obesity and Metabolism. Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross‐over trial

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